Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration Kirsch I, Deacon BJ, Huedo-Medina TB, Scoboria A, Moore TJ, et al. PLoS Medicine Vol. 5, No. 2, e45 doi:10.1371/journal.pmed.0050045
Drug-placebo differences in antidepressant efficacy increase as a function of baseline severity, but are relatively small even for severely depressed patients. The relationship between initial severity and antidepressant efficacy is attributable to decreased responsiveness to placebo among very severely depressed patients, rather than to increased responsiveness to medication.
Now who thinks this will actually stop doctors from fucking over many of my friends and colleagues?
Give your doctor a notepad to write on. Give them a pen. Given them a fluffy toy and a mousepad. Give them some patient data tracking software that doesn't display ads . Doctors are so poor, they have to sell their patients to drug companies just to have these necessary things.
And give them a copy of this paper.
 Not joking. At least at Monash University, the GPs use patient data tracking software that displays drug ads.